Local graffiti artist, Trik09, created the seven-foot mural in Division Street in tribute to Bowie after his death from cancer in 2016.
But on Monday, July 18, locals drove through town to find that builders had begun removing the mural by chiseling away the masonry underneath.
The wall was completely bare the next morning.
The David Bowie mural on the corner of Trafalgar Street – which some critics have mocked saying looks more like Pat Sharp. Nevertheless, he was loved by many.
The mural was met with ironic criticism upon its unveiling, with people on social media claiming it looked more like TV presenter Pat Sharp.
A Twitter user at the time said: ‘A new idea would be to have a photo that looks like Bowie – whose photo is that?
It is understood the facelift is just one step in a plan by environmentalists to update the street.
The David Bowie mural has now been removed, leaving only the bare brick below.
A member of the public said: “It’s really a shame. It’s not very good for the area.
“Modernization is taking over.
Another Sheffield resident said: ‘It was part of the street walk and it’s really weird to have it missing.
“I didn’t know they were getting rid of it, it’s pretty sad.”
The mural has been displayed on the side of the Mint clothing store on the corner of Trafalgar Street for more than six years.
Awal Yusoff, who has worked at Mint for 15 years, said: “The mural is part of Division Street, its identity. I liked it.”
The owners of the building have been contacted for comment.